Cell and Gene Therapy

The latest in translation, clinical development and commercialisation of cell and gene therapies.

Cell and Gene Therapy
19/02/2018

This collaborative case study with Fisher BioServices and SOTIO describes the use of dispersed storage and cold chain logistics, around a central manufacturing facility to create a cost-efficient and robust supply chain.

 

supply chain case study part five commercialisation
Cell and Gene Therapy
19/02/2018

This case study examines the challenge of scaling cryogenic storage and management to mitigate quality risks and address increased throughput needs.

 

Scaling a manual process is a challenge in a regulated environment...

supply chain case study part 4 cryopreservation Brooks Automation
Cell and Gene Therapy
19/02/2018

The third case study in the series, in partnership with World Courier, describes the highly complex logistics needs of an autologous immunotherapy that involves collection from over 90 apheresis centres and delivery of the therapy to over 170 clin...

supply chain case study part 3 transportation world courier
Cell and Gene Therapy
19/02/2018

TrakCel's case study showcases the journey of TCR Catapult's (a consortium of the Cell and Gene Therapy Catapult, UCL and Imperial College) gene-modified T-cell receptor therapy targeting WT1-overexpressing cells. 

Several chal...

supply chain case study Fibrocell
Cell and Gene Therapy
19/02/2018

This case study presents an injectable autologous adult human dermal fibroblast product and its associated manufacturing and supply chain challenges, which include:

  • Inventory and tracking controls for many small individual produc...
Supply Chain Case study Part 1: Supply Chain Planning TrakCel
Cell and Gene Therapy
15/02/2018

Over the past few decades, many lessons have been learnt by the wider biological medicinal product community when it comes to preventing transmission of viral infections. The World Federation of Haemophilia’s mantra of ‘never again’ is still...

Viral Safety for advanced therapy medicinal products
Cell and Gene Therapy
01/02/2018

Cell, gene and immuno-oncology therapies provide the biggest potential for previously incurable conditions and are the future of medicine and healthcare. The complexity of these therapeutics poses challenges for those developing these products, pa...

Advanced Therapies 2025 by Phacilitate
Cell and Gene Therapy
23/01/2018

The pace of innovation across cell and gene therapy biotechs is gaining speed and it can be challenging to keep track of scientific developments, new technologies and who might be looking for their next big partnership.

Top 15 cell and gene therapy biotechs to watch in 2018
Cell and Gene Therapy
22/01/2018

Manufacturing and process development for cell and gene therapies is growing rapidly in Europe…but so is demand.

Ensuring enough manufacturing capacity is now critical,

An often overlooked but major challenge of the supply chain in addition to these factors is the ‘when’. When is the optimum time to start designing your supply chain and how will it look in relation to your clinical supply chain? One of the mo...

Cell and Gene Therapy
11/01/2018

Successful development of advanced therapies relies on robust CRO partnerships but the industry is facing huge challenges with identifying and selecting the right partner with the right expertise.

 

This infographic provid...